Roshel supports medicinal chemistry and scalable process development.
Milestone-driven collaboration, practical synthesis support, and transparent reporting stay central throughout every engagement.
Medicinal Chemistry
At Roshel, our Medicinal Chemistry team is dedicated to transforming innovative ideas into therapeutic realities. By combining deep expertise in chemistry with cutting-edge drug discovery technologies, we design and optimize small molecules that address some of the most challenging medical conditions.
In this service, Roshel usually contributes to improving the synthesis, providing alternate routes thereby assisting in expediting the delivery of the target compounds. Additionally, the client gets periodical access to the progress made and interacts with the team through regular web meetings. After reaching the milestone, Roshel submits comprehensive experimental procedures that are immediately applicable to publications and patents, followed by a final project report.
- Targeted drug design using structure-based design, computational modeling, and screening insights.
- Lead optimization to improve potency, pharmacokinetics, and drug-like properties.
- Collaborative innovation with cross-functional teams to create a clearer bench-to-bedside path.
Process Development
Roshel specializes in process development that transforms ideas into efficient, scalable, and high-performing operations. Our team combines technical expertise, industry best practices, and innovative problem-solving to optimize every step from concept design to full-scale implementation.
This service often starts with route scouting in which the Roshel team proposes the maximum number of synthetic routes for a given molecule. For prioritized schemes, feasibility studies and process optimization are systematically undertaken. The best process is usually subjected to a scale-up exercise at 1 to 10 kg scale, ultimately culminating in a detailed technology transfer package.
- Route scouting and route prioritization for target molecules.
- Feasibility studies and process optimization for robust execution.
- Scale-up support from 1 kg to 10 kg as proof of concept.
- Technology transfer documentation with complete findings and implementation guidance.